化工社化工社 化学情報印刷レポート · 研究参考用
N-methylcyclopentanamine → N-(4-pyridazinyl)-N'-cyclopentyl-N'-methylurea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-methylcyclopentanamine | HCID 7020624 | — |
| 反応物 | Phenyl pyridazin-4-ylcarbamate | HCID 14099147 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | N-(4-pyridazinyl)-N'-cyclopentyl-N'-methylurea | HCID 20150035 | — |
反応手順
A stirred solution of 2.0 grams of phenyl N-(4-pyridazinyl)carbamate (prepared as in Example 2, Step A) and 0.9 gram of N-cyclopentyl-N-methyl amine in tetrahydrofuran is heated under reflux for 18 hours. The reaction mixture is filtered and the filtrate concentrated under reduced pressure to a residue. The residue is purified by column chromatography on silica gel to yield N-(4-pyridazinyl)-N'-cyclopentyl-N'-methylurea.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04728355 |
| 出典データセット | uspto-grants-1988_03 |
| ORD ID | ord-4f364a08bbb1497aba4f90badbd625b0 |
| 出典メモ | uspto-grants-1988_03 |