Thionyl Chloride → HCID 13878422、化合物

HRID 568756ノート

反応式

HRID 568756 の反応式
S(Cl)([Cl:3])=O.[CH3:5][CH:6]([O:13][C:14]1[CH:22]=[CH:21][C:17]([C:18](O)=[O:19])=[CH:16][CH:15]=1)[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]>>[CH3:5][CH:6]([O:13][C:14]1[CH:22]=[CH:21][C:17]([C:18]([Cl:3])=[O:19])=[CH:16][CH:15]=1)[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 13878419p-(1-Methyl-heptyloxy)benzoic acid

生成物 1

HCID 13878422HCID 13878422、化合物収率 93%

実験手順

Thionyl chloride (51.2 g, 0.43 mol) was added to optically active p-(1-methyl-heptyloxy)benzoic acid (90.0 g, 0.36 mol), followed by refluxing the mixture for about 2 hours, thereafter completely removing excess thionyl chloride by distillation under reduced pressure to obtain optically active p-(1-methyl-heptyloxy)benzoic acid chloride (90.0 g).

後処理

  1. temperatureby refluxing the mixture for about 2 hours
  2. distillationcompletely removing excess thionyl chloride by distillation under reduced pressure

出典と根拠

ORDレコード
ord-a514f906415d486db0b095e432061e79
出典データセット
uspto-grants-1988_03
特許番号
US04729847

反応ノート

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