(3aR,5R,6aR)-Benzyl 5-((3-methoxytetrahydro-2H-pyran-4-yl)amino)-3a-(3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carbonyl)hexahydrocyclopenta-[c]pyrrole-2(1H)-carboxylate → ((3aR,5R,6aR)-5-(((3S*,4S*)-3-Methoxytetrahydro-2H-pyran-4-yl)amino)octahydro-cyclopenta[c]pyrrol-3a-yl)(3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)methanone
反応式
[CH3:1][O:2][CH:3]1[CH:8]([NH:9][C@@H:10]2[CH2:27][C@H:13]3[CH2:14][N:15](C(OCC4C=CC=CC=4)=O)[CH2:16][C@@:12]3([C:28]([N:30]3[CH2:39][CH2:38][C:37]4[N:36]=[CH:35][C:34]([C:40]([F:43])([F:42])[F:41])=[CH:33][C:32]=4[CH2:31]3)=[O:29])[CH2:11]2)[CH2:7][CH2:6][O:5][CH2:4]1>CO.[Pd]>[CH3:1][O:2][C@H:3]1[C@@H:8]([NH:9][C@@H:10]2[CH2:27][C@H:13]3[CH2:14][NH:15][CH2:16][C@@:12]3([C:28]([N:30]3[CH2:39][CH2:38][C:37]4[N:36]=[CH:35][C:34]([C:40]([F:43])([F:41])[F:42])=[CH:33][C:32]=4[CH2:31]3)=[O:29])[CH2:11]2)[CH2:7][CH2:6][O:5][CH2:4]1参加物
4
