Trifluoroacetic acid → 4-{3-(cyanomethyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-1-yl}-N-[(1R)-1-cyclopropylethyl]-2,5-difluorobenzamide

反応式

[C:1]([CH2:3][C:4]1([N:24]2[CH:28]=[C:27]([C:29]3[C:30]4[CH:37]=[CH:36][N:35](COCC[Si](C)(C)C)[C:31]=4[N:32]=[CH:33][N:34]=3)[CH:26]=[N:25]2)[CH2:7][N:6]([C:8]2[C:21]([F:22])=[CH:20][C:11]([C:12]([NH:14][C@@H:15]([CH:17]3[CH2:19][CH2:18]3)[CH3:16])=[O:13])=[C:10]([F:23])[CH:9]=2)[CH2:5]1)#[N:2].FC(F)(F)C(O)=O>C(Cl)Cl>[C:1]([CH2:3][C:4]1([N:24]2[CH:28]=[C:27]([C:29]3[C:30]4[CH:37]=[CH:36][NH:35][C:31]=4[N:32]=[CH:33][N:34]=3)[CH:26]=[N:25]2)[CH2:7][N:6]([C:8]2[C:21]([F:22])=[CH:20][C:11]([C:12]([NH:14][C@@H:15]([CH:17]3[CH2:18][CH2:19]3)[CH3:16])=[O:13])=[C:10]([F:23])[CH:9]=2)[CH2:5]1)#[N:2]