Hydrochloric Acid → HCID 557334、化合物
反応式
[OH-].[K+].[C:3]([O:12]CC)(=[O:11])[CH2:4][CH2:5][CH:6]=[CH:7][CH:8]=[CH:9][CH3:10].Cl>CCCCCCC>[C:3]([OH:12])(=[O:11])[CH2:4][CH2:5][CH:6]=[CH:7][CH:8]=[CH:9][CH3:10]参加物
5
反応条件
- 温度
- 45 °C
実験手順
A20% aqueous solution of potassium hydroxide (477 g, 1.7 mol) and ethyl 4,6-octadienoate (c) (114.4 g, 0.68 mol) were put into a four-neck flask, followed by stirring at 45° C. for 3 hours. The reaction solution was cooled to room temperature, heptane (230 mL) was added thereto, and 35% hydrochloric acid (177 g) was added dropwise thereto. After separation of liquid, the organic layer was washed with water (230 mL), and the solvent was evaporated therefrom under a reduced pressure. Thus, 4,6-octadienoic acid (d) was obtained (90.6 g, yield 95%).
後処理
- temperatureThe reaction solution was cooled to room temperature
- customAfter separation of liquid
- washthe organic layer was washed with water (230 mL)
- customthe solvent was evaporated
出典と根拠
- ORDレコード
- ord-68d95bf153d845e38ec97b39911fc4db
- 出典データセット
- uspto-grants-2015_05
- 特許番号
- US09029593B2
反応ノート
読み込み中…