Trifluoroacetic acid → HCID 68380761、化合物
反応式
[CH3:1][C:2]1[CH:3]=[C:4]([NH2:22])[C:5]2[C:10]([C:11]3[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[CH:12]=3)=[C:9]([CH:19]([CH3:21])[CH3:20])[S:8][C:6]=2[N:7]=1.[CH3:23][N:24]1[CH:28]=[C:27]([S:29](Cl)(=[O:31])=[O:30])[N:26]=[CH:25]1.[C:33]([OH:39])([C:35]([F:38])([F:37])[F:36])=[O:34]>>[F:36][C:35]([F:38])([F:37])[C:33]([OH:39])=[O:34].[CH3:23][N:24]1[CH:28]=[C:27]([S:29]([NH:22][C:4]2[CH:3]=[C:2]([CH3:1])[N:7]=[C:6]3[S:8][C:9]([CH:19]([CH3:20])[CH3:21])=[C:10]([C:11]4[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[CH:12]=4)[C:5]=23)(=[O:31])=[O:30])[N:26]=[CH:25]1参加物
4
実験手順
Following general method outlined in Example 1, starting from 6-methyl-2-(1-methylethyl)-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-amine (60 mg, 0.192 mmol) (Description 21) and 1-methyl-1H-imidazole-4-sulfonyl chloride (69.4 mg, 0.384 mmol), the title compound (37 mg) was isolated as a TFA salt. LCMS (B) m/z: 457 [M+1]+, Rt 2.85 min.
出典と根拠
- ORDレコード
- ord-f025a34cd4de42bfab21894fd8d8c29b
- 出典データセット