Thionyl Chloride → 4-Methylnaphthalene-1-carbonyl chloride

HRID 574598

反応式

HRID 574598 の反応式
[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([C:12]([OH:14])=O)=[CH:4][CH:3]=1.S(Cl)([Cl:17])=O>ClCCl>[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([C:12]([Cl:17])=[O:14])=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 30142854-Methyl-1-naphthalenecarboxylic acid

生成物 1

HCID 248874124-Methylnaphthalene-1-carbonyl chloride

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a solution of 0.35 g (1.89 mmol) of 4-methyl-1-napthoic acid in 3 mL of dry dichloromethane under argon, was added 2.5 ml (34.3 mmol) of thionyl chloride. The solution was refluxed for 4 hrs and the solvent and excess thionyl chloride were removed by vacuum distillation to give a red oil, which was used without further purification.

後処理

  1. temperatureThe solution was refluxed for 4 hrs
  2. customthe solvent and excess thionyl chloride were removed by vacuum distillation
  3. customto give a red oil, which
  4. customwas used without further purification

出典と根拠

ORDレコード
ord-e7bf472ec26c4ba8bd4fa69a29f493ff
出典データセット
uspto-grants-2015_05
特許番号
US09034895B2

関連ノート

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