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Hydrochloric Acid → HCID 178526812、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 2-Phenylmethoxyethanimidamide | HCID 416406 | — |
| 反応物 | ethyl 2-(N,N-dimethylaminomethylene)nitroacetate | HCID 54330941 | — |
| 反応物 | HCID 178418582 | HCID 178418582 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | HCID 178526812 | HCID 178526812 | — |
反応手順
To a mixture of step A product, 3-c, (24 g, 127 mmol) and 2-(benzyloxy)acetimidamide (25.9 g, 127 mmol) in CH3OH (30 mL) was added with NaOCH3 (14.2 g, 254 mmol) and 30° C. overnight. The pH of reaction mixture was adjusted to 7 by addition of concentrated HCl. The solids were filtered to afford the crude product, 3-d, (25 g). LC-MS (M+H)+ 262.1
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09034851B2 |
| 出典データセット | uspto-grants-2015_05 |
| ORD ID | ord-1eabca45e50047359115534ed1968bc6 |
| 出典メモ | uspto-grants-2015_05 |