6-((Dibenzylamino)methyl)morpholin-3-one → 6-(Aminomethyl)morpholin-3-one
反応式
C([N:8]([CH2:16][CH:17]1[CH2:22][NH:21][C:20](=[O:23])[CH2:19][O:18]1)CC1C=CC=CC=1)C1C=CC=CC=1>CCO.[OH-].[OH-].[Pd+2]>[NH2:8][CH2:16][CH:17]1[CH2:22][NH:21][C:20](=[O:23])[CH2:19][O:18]1参加物
4
実験手順
A solution of 6-((dibenzylamino)methyl)morpholin-3-one (340 mg, 1.09 mmol), Pd(OH)2/C (170 mg) in EtOH (30 mL) was stirred equipped under H2 balloon overnight. The solution was filtered and concentrated to give white oil. The crude product was used directly for next step without purification.
後処理
- customequipped under H2 balloon overnight
- filtrationThe solution was filtered
- concentrationconcentrated
- customto give white oil
- customThe crude product was used directly for next step without purification
出典と根拠
- ORDレコード
- ord-bbc83b480d1644d2811adaf60dc45bb8
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09434726B2
反応ノート
読み込み中…