1,3-Benzodioxole, 5-ethenyl- → 5-Ethylbenzo[d][1,3]dioxole
反応式
[CH:1]([C:3]1[CH:11]=[CH:10][C:6]2[O:7][CH2:8][O:9][C:5]=2[CH:4]=1)=[CH2:2]>CO.[Pd]>[CH2:1]([C:3]1[CH:11]=[CH:10][C:6]2[O:7][CH2:8][O:9][C:5]=2[CH:4]=1)[CH3:2]参加物
4
実験手順
A mixture of 5-vinylbenzo[d][1,3]dioxole (6.0 g, 40.5 mmol) and 10% Pd/C (840 mg) in MeOH (50 mL) was hydrogenated for 8 h at 10 atm. Then Pd/C was filtered and the MeOH was removed to give compound 5-ethylbenzo[d][1,3]dioxole (3.0 g, 50%) as colorless liquid. 1H-NMR (DMSO-d6): δ 1.11 (t, 3H, J=7.2 Hz), 2.50 (q, 2H, J1=7.2 Hz, J2=16 Hz), 5.93 (s, 2H), 6.64 (d, 1H, J=8 Hz), 6.77 (m, 2H).
後処理
- filtrationThen Pd/C was filtered
- customthe MeOH was removed
出典と根拠
- ORDレコード
- ord-b2c81bf1b26149e0bb6b974a8bbd088d
- 出典データセット
- uspto-grants-2015_05
- 特許番号
- US09040556B2
反応ノート
読み込み中…