1-tert-butyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → tert-butyl 4-(6-(6-(1-tert-butyl-1H-pyrazol-4-yl)-1H-pyrazolo[4,3-c]pyridin-1-yl)pyridin-2-yl)-1,4-diazepane-1-carboxylate

反応式

[C:1]([N:5]1[CH:9]=[C:8](B2OC(C)(C)C(C)(C)O2)[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2].Cl[C:20]1[N:25]=[CH:24][C:23]2[CH:26]=[N:27][N:28]([C:29]3[N:34]=[C:33]([N:35]4[CH2:41][CH2:40][CH2:39][N:38]([C:42]([O:44][C:45]([CH3:48])([CH3:47])[CH3:46])=[O:43])[CH2:37][CH2:36]4)[CH:32]=[CH:31][CH:30]=3)[C:22]=2[CH:21]=1>O1CCOCC1.C([O-])([O-])=O.[Na+].[Na+].C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>[C:1]([N:5]1[CH:9]=[C:8]([C:20]2[N:25]=[CH:24][C:23]3[CH:26]=[N:27][N:28]([C:29]4[N:34]=[C:33]([N:35]5[CH2:41][CH2:40][CH2:39][N:38]([C:42]([O:44][C:45]([CH3:48])([CH3:47])[CH3:46])=[O:43])[CH2:37][CH2:36]5)[CH:32]=[CH:31][CH:30]=4)[C:22]=3[CH:21]=2)[CH:7]=[N:6]1)([CH3:2])([CH3:3])[CH3:4]