tert-butyl N-[(3S)-piperidin-3-yl]carbamate → (S)-3-(3-Aminopiperidin-1-yl)-1-methyl-5-(6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[4,3-c]pyridin-1-yl)pyrazin-2(1H)-one
反応式
[NH:1]1[CH2:6][CH2:5][CH2:4][C@H:3]([NH:7]C(=O)OC(C)(C)C)[CH2:2]1.Br[C:16]1[C:17](=[O:24])[N:18]([CH3:23])[CH:19]=[C:20](Br)[N:21]=1.Cl[C:26]1[N:31]=[CH:30][C:29]2[CH:32]=[N:33][NH:34][C:28]=2[CH:27]=1.[CH3:35][N:36]1[CH:40]=[C:39](B2OC(C)(C)C(C)(C)O2)[CH:38]=[N:37]1>>[NH2:7][C@H:3]1[CH2:4][CH2:5][CH2:6][N:1]([C:16]2[C:17](=[O:24])[N:18]([CH3:23])[CH:19]=[C:20]([N:34]3[C:28]4[CH:27]=[C:26]([C:39]5[CH:38]=[N:37][N:36]([CH3:35])[CH:40]=5)[N:31]=[CH:30][C:29]=4[CH:32]=[N:33]3)[N:21]=2)[CH2:2]1参加物
5
