Ethylene Oxide → 2-(Hexylamino)ethanol

反応式

[CH2:1]([CH:7]([CH2:9][NH2:10])O)[CH2:2][CH2:3][CH2:4]CC.C(N)CCCCC.[CH2:18]1[O:20][CH2:19]1>>[CH2:9]([NH:10][CH2:18][CH2:19][OH:20])[CH2:7][CH2:1][CH2:2][CH2:3][CH3:4]

参加物

反応物 3

HCID 6354Ethylene Oxide2 回

HCID 8102Hexylamine2 回

HCID 3450531-Aminooctan-2-ol

生成物 1

HCID 1086102-(Hexylamino)ethanol

実験手順

In an alternate synthesis scheme for n-hexyl ethanolamine, the ethoxylation steps remained the same as above in sequence, temperature and pressure. However, the preferred weight fraction of n-hexyl amine to ethylene oxide was lowered to approximately 88 pounds n-hexyl amine to 12 pounds ethylene oxide to yield 100 pounds of reaction mass. The weight ratio of mono to di ethoxylates in the reaction mass was approximately 4.0-4.2 mono to 1.0 di. The purification section was also the same except the process was stopped after removal of n-hexyl amine overhead. The final bottoms fraction contained n-hexyl ethanolamine and some diethoxylates byproducts (less than 20% by weight).