Methanol → AC-Pro-ome

HRID 579831

反応式

HRID 579831 の反応式
CCCCCCCCCCCCCCC.C[OH:17].[C:18]([N:21]1[CH2:25][CH2:24][CH:23]=[CH:22]1)(=[O:20])[CH3:19].[O:26]1[CH2:30]CC[CH2:27]1>>[CH3:27][O:26][C:30](=[O:17])[C@@H:22]1[CH2:23][CH2:24][CH2:25][N:21]1[C:18](=[O:20])[CH3:19]

参加物

5

反応物 4

HCID 887MethanolHCID 8028TetrahydrofuranHCID 12391PentadecaneHCID 10909522N-Acetyl-2-pyrroline2 回

生成物 1

HCID 11019314AC-Pro-ome収率 1.1%

反応条件

温度
100 °C

実験手順

A 70 mL stainless steel high pressure reactor having a Pyrex glass liner and a magnetic stir bar was charged with 5 mL of tetrahydrofuran, 0.5 mmol of n-pentadecane internal standard, 0.5 mmol of CH3OH, 4.88 mg of Fe(CO)5, and 57.19 mg of N-acetyl-2-pyrroline. The reactor was pressurized to 1000 psi with CO at room temperature, and the reaction mixture was stirred at 100° C. for 21 hours. Thereafter, the reactor was cooled to room temperature and vented to atmospheric pressure. The product mixture was analyzed by gas chromatography, and the analysis indicated 86.7% conversion of N-acetyl-2-pyrroline and 1.1% yield of N-acetylproline methyl ester.

後処理

  1. customA 70 mL stainless steel high pressure reactor having
  2. customwas pressurized to 1000 psi with CO at room temperature
  3. temperatureThereafter, the reactor was cooled to room temperature

出典と根拠

ORDレコード
ord-4d8e1cb8d2074a76818758a2f5464a3c
出典データセット
uspto-grants-1988_06
特許番号
US04749786

関連ノート

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