Thionyl Chloride → HCID 13340573、化合物

HRID 580999ノート

反応式

HRID 580999 の反応式
S(Cl)([Cl:3])=O.[I:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][C:13]([OH:15])=O)=[CH:8][CH:7]=1>CN(C=O)C.ClCCl>[I:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][C:13]([Cl:3])=[O:15])=[CH:8][CH:7]=1

参加物

5

反応物 2

HCID 24386Thionyl ChlorideHCID 1372144-Iodophenylacetic acid

生成物 1

HCID 13340573HCID 13340573、化合物

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 6344Dichloromethane溶媒

実験手順

Thionyl chloride (39.53) and DMF (2 drops) were added to a solution of 4-iodophenylacetic acid (26.2 g), in dichloromethane (150 ml). The reaction mixture was stirred at ambient temperature for 18 hours and the solvent removed by evaporation to give 4-iodophenylacetyl chloride as an oil (23 g) which was purified by vacuum distillation; b.p. 118-119° C. (0.35 mmMg)

後処理

  1. customthe solvent removed by evaporation

出典と根拠

ORDレコード
ord-17579de340d84bff8ef4873a7016403c
出典データセット
uspto-grants-1999_07
特許番号
US05919793

反応ノート

読み込み中…