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Hydrochloric Acid → 2-Amino-5-methoxybenzene-1-thiol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | 2-Amino-6-methoxybenzothiazole | HCID 15630 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-Amino-5-methoxybenzene-1-thiol | HCID 235509 | — |
反応手順
34.3 g (0.19 mol) of 2-amino-6-methoxy-benzothiazole and 140 g (2.5 mol) of 85% potassium hydroxide are refluxed in 350 ml of water for 5 hours. Then the mixture is cooled and neutralised with 200 ml of concentrated hydrochloric acid. The mixture is stirred for a further 30 minutes, the precipitate formed is suction filtered, washed with water and dried in vacuo. Yield: 24.0 g (81.4% of theory). The following is obtained analogously to Example B:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05919807 |
| 出典データセット | uspto-grants-1999_07 |
| ORD ID | ord-1b43938fb5074402905e3d3e73f51a4f |
| 出典メモ | uspto-grants-1999_07 |