関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Nitric Acid | HCID 944 | — |
| 反応物 | 4'-Bromoacetanilide | HCID 7683 | — |
| 溶媒 | Methanesulfonic Acid | HCID 6395 | — |
| 生成物 | N-(4-bromo-2-nitrophenyl)acetamide | HCID 136690 | — |
反応手順
A solution of 4-bromoacetanilide (20 g, 93.4 mmol) in methanesulfonic acid is cooled to 10° C. Conc. nitric acid (12.6 ml) is added and the mixture is stirred at 40° C. for 2 hours. The mixture is poured into ice-water. The product is filtered off, washed with water and dried. Yield: 23.59 g (97%). Mp 99-100° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05922724 |
|---|
| 出典データセット | uspto-grants-1999_07 |
|---|
| ORD ID | ord-8d0de64f9359453cae0c0c6038f3b65f |
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| 出典メモ | uspto-grants-1999_07 |
|---|
