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HRID581948

反应详情

EQUATION

反应方程式

HRID 581948 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])O
HCID944

Nitric Acid

HNO3

结构：CC(=O)Nc1ccc(Br)cc1
HCID7683

Acetamide, N-(4-bromophenyl)-

C8H8BrNO

PRODUCTS

生成物

1
结构：CC(=O)Nc1ccc(Br)cc1[N+](=O)[O-]
HCID136690

4'-Bromo-2'-nitroacetanilide

C8H7BrN2O3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CS(=O)(=O)O
溶剂HCID6395

Methanesulfonic acid

CH4O3S

CONDITIONS

反应条件

温度
40 °C

PROCEDURE

实验过程

A solution of 4-bromoacetanilide (20 g, 93.4 mmol) in methanesulfonic acid is cooled to 10° C. Conc. nitric acid (12.6 ml) is added and the mixture is stirred at 40° C. for 2 hours. The mixture is poured into ice-water. The product is filtered off, washed with water and dried. Yield: 23.59 g (97%). Mp 99-100° C.

WORKUP

后处理

  1. filtrationThe product is filtered off
  2. washwashed with water
  3. customdried