関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Aniline | HCID 6115 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 2-Furancarbonyl chloride | HCID 68242 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | N-Phenyl-2-furancarboxamide | HCID 220406 | — |
反応手順
N-phenyl furamide was prepared by adding to a mixture of aniline (23.3 g; 250 mmol) and triethylamine (25.3 g; 250 mmol) in dichloromethane slowly 32.6 g (250 mmol) of 2-furoyl chloride, while maintaining the temperature at -10° C. The product obtained was washed with diluted hydrochloric acid and water, dried with magnesium sulphate and evaporated. The product so obtained was than triturated with hexane and filtered. 39.3 g (84% yield of product was recovered.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05925152 |
|---|
| 出典データセット | uspto-grants-1999_07 |
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| ORD ID | ord-ec294cbabf8b4576be6a8b4d93a811ec |
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| 出典メモ | uspto-grants-1999_07 |
|---|
