Water → 3-(Oxiran-2-yl)propyl 2-methylprop-2-enoate

HRID 582443ノート

反応式

HRID 582443 の反応式
[C:1]([O:6][CH2:7][CH2:8][CH2:9][CH:10]=[CH2:11])(=[O:5])[C:2]([CH3:4])=[CH2:3].C1C=C(Cl)C=C(C(OO)=[O:20])C=1.O>C(Cl)Cl>[C:1]([O:6][CH2:7][CH2:8][CH2:9][CH:10]1[O:20][CH2:11]1)(=[O:5])[C:2]([CH3:4])=[CH2:3]

参加物

5

反応物 3

HCID 962WaterHCID 70297m-Chloroperbenzoic acidHCID 20163830HCID 20163830、化合物

生成物 1

HCID 220966403-(Oxiran-2-yl)propyl 2-methylprop-2-enoate

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

A solution of 4-pentenyl methacrylate (9 g) in methylene dichloride (15 ml) was added to a solution of m-CPBA (18 g) in methylene dichloride (150 ml) and the reaction was allowed to proceed for 5 hr. The reaction mixture was then poured into water, the organic phase was separated and then washed several times with a dilute solution of potassium carbonate. The reaction product was washed with water and then dried with anhydrous magnesium sulfate. A pure product was isolated by column chromatography on silica gel. Yield 7 g.

後処理

  1. customthe organic phase was separated
  2. washwashed several times with a dilute solution of potassium carbonate
  3. washThe reaction product was washed with water
  4. dry with materialdried with anhydrous magnesium sulfate
  5. customA pure product was isolated by column chromatography on silica gel

出典と根拠

ORDレコード
ord-9618e77e2a0c4193bad9f502a3f091f1
出典データセット
uspto-grants-1999_07
特許番号
US05925253

反応ノート

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