Cyclopropylamine → HCID 15220200、化合物
反応式
[CH:1]1([NH2:4])[CH2:3][CH2:2]1.[Cl:5][C:6]1[C:7]([C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[C:18]([S:23](Cl)(=[O:25])=[O:24])[CH:17]=2)=[N:8][N:9]([CH3:15])[C:10]=1[O:11][CH:12]([F:14])[F:13]>O1CCCC1>[Cl:5][C:6]1[C:7]([C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[C:18]([S:23]([NH:4][CH:1]3[CH2:3][CH2:2]3)(=[O:24])=[O:25])[CH:17]=2)=[N:8][N:9]([CH3:15])[C:10]=1[O:11][CH:12]([F:14])[F:13]参加物
4
実験手順
0.9 g (16 mmol) of cyclopropylamine was added to a solution of 3 g (7.6 mmol) of 4-chloro-3-(4-chloro-3-chlorosulfonylphenyl)-5-difluoromethoxy-1-methyl-1H-pyrazole in 25 ml of tetrahydrofuran. The mixture was stirred at room temperature for 4 hours and then concentrated to dryness. The solid residue was washed with a little diisopropyl ether. Yield: 3 g.
後処理
- concentrationconcentrated to dryness