Ammonium Hydroxide → HCID 21584299、化合物

HRID 583256ノート

反応式

HRID 583256 の反応式
[CH2:1]1[CH:10]2[N:5]([C:6](=[O:15])[C:7]3[CH:14]=[CH:13][CH:12]=[CH:11][C:8]=3[CH2:9]2)[CH2:4][CH2:3][CH2:2]1.[N+:16]([O-])([O-:18])=[O:17].[K+].[OH-].[NH4+]>S(=O)(=O)(O)O>[N+:16]([C:13]1[CH:12]=[CH:11][C:8]2[CH2:9][CH:10]3[N:5]([C:6](=[O:15])[C:7]=2[CH:14]=1)[CH2:4][CH2:3][CH2:2][CH2:1]3)([O-:18])=[O:17]

参加物

5

反応物 3

HCID 14923Ammonium HydroxideHCID 24434Potassium NitrateHCID 27527926H-Benzo[b]quinolizin-6-one, 1,2,3,4,11,11a-hexahydro-

生成物 1

HCID 21584299HCID 21584299、化合物収率 92%

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

1,3,4,6,11,11a-Hexahydro-2H-benzo[b]quinolizin-6-one (3.78 g, 18.7 mmol) was dissolved in concentrated sulfuric acid (50 ml) at 0° C., potassium nitrate (2.02 g, 20 mmol) was added and the reaction mixture was stirred overnight. The reaction mixture was poured onto ice (200 g) and was partially neutralized with concentrated ammonium hydroxide. The precipitate was collected and air-dried to give the title compound as a yellow solid (4.22 g, 92%), m.p. 137-42° C.

後処理

  1. additionThe reaction mixture was poured onto ice (200 g)
  2. customThe precipitate was collected
  3. customair-dried

出典と根拠

ORDレコード
ord-c2d9d7ced0324aeb98d237805c14bbec
出典データセット
uspto-grants-1999_07
特許番号
US05929085

反応ノート

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