関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Butyric anhydride | HCID 7798 | — |
| 反応物 | 7-(2-Chloro propenyl)-4-methyl coumarin | HCID 91010456 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 8-Chloropropenyl-7-hydroxy-4-methylcoumarin | HCID 87976573 | — |
反応手順
A solution of 7-(2-chloro propenyl)-4-methyl coumarin (120 g, 0.48 mol) in a mixture of p-disopropyl-benzene (1L) and n-butyric anhydride 160 mL was heated to 180° C. for 24 hours. The organic layer was evaporated under reduced pressure and residue recrystallizated from ethanol to afford 75 g of the desired compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06924373B2 |
|---|
| 出典データセット | uspto-grants-2005_08 |
|---|
| ORD ID | ord-e8132dcc1fcc445ea1f151daa2899dad |
|---|
| 出典メモ | uspto-grants-2005_08 |
|---|
