2-Bromo-1-ethyl-4-nitrobenzene → 3-Bromo-4-ethylaniline
反応式
[Br:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[CH2:11][CH3:12]>[Fe]>[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[CH:5]=[CH:4][C:3]=1[CH2:11][CH3:12]参加物
3
実験手順
In a manner similar to that of Example 1(c), by reacting 34 g (148 mmol) of 1-bromo-2-ethyl-5-nitrobenzene with 33 g (591 mmol) of iron, and after purification by chromatography on a column of silica eluted with a mixture of heptane and ethyl acetate (90/10), 27 g (89%) of the expected product are obtained in the form of a yellow oil.
後処理
- customafter purification by chromatography on a column of silica
- washeluted with a mixture of heptane and ethyl acetate (90/10), 27 g (89%) of the expected product
- customare obtained in the form of a yellow oil
出典と根拠
- ORDレコード
- ord-a492d50b550847aba890ac5ecce3dfd8
- 出典データセット
- uspto-grants-2005_08
- 特許番号
- US06924400B2
反応ノート
読み込み中…