(3-Bromo-4-methylphenyl)methanol → 3-Bromo-4-methylbenzaldehyde

HRID 584312

反応式

HRID 584312 の反応式
[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][OH:10])[CH:5]=[CH:6][C:7]=1[CH3:8]>ClCCl.[O-2].[Mn+2]>[Br:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][C:7]=1[CH3:8])[CH:9]=[O:10]

参加物

4

反応物 1

HCID 12947381(3-Bromo-4-methylphenyl)methanol

生成物 1

HCID 8167653-Bromo-4-methylbenzaldehyde収率 85%

試薬・触媒・溶媒 2

HCID 160959Manganese oxide触媒HCID 6344Dichloromethane溶媒

実験手順

14.4 g (72 mmol) of (3-bromo-4-methylphenyl)methanol are placed in 200 ml of dichloromethane in a round-bottomed flask. 62.6 g (72 mmol) of manganese oxide are added and the medium is stirred at room temperature overnight. The mixture is filtered through Celite and the solvent is evaporated off. 11.8 g (85%) of the expected product are obtained in the form of an oil.

後処理

  1. filtrationThe mixture is filtered through Celite
  2. customthe solvent is evaporated off

出典と根拠

ORDレコード
ord-20172710c0904141ac8730fb33bb8ee2
出典データセット
uspto-grants-2005_08
特許番号
US06924400B2

関連ノート

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