Hydrogen Bromide → 2-(3,4-Dichlorophenyl)-6,7-dinitroquinoxaline

HRID 584676

反応式

HRID 584676 の反応式
Br.[CH3:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([Cl:12])[CH:6]=1)=O.[N+:13]([C:16]1[C:21]([N+:22]([O-:24])=[O:23])=[CH:20][C:19]([NH2:25])=[C:18]([NH2:26])[CH:17]=1)([O-:15])=[O:14]>CS(C)=O>[Cl:12][C:7]1[CH:6]=[C:5]([C:3]2[CH:2]=[N:26][C:18]3[C:19](=[CH:20][C:21]([N+:22]([O-:24])=[O:23])=[C:16]([N+:13]([O-:15])=[O:14])[CH:17]=3)[N:25]=2)[CH:10]=[CH:9][C:8]=1[Cl:11]

参加物

5

反応物 3

HCID 260Hydrogen BromideHCID 75841Ethanone, 1-(3,4-dichlorophenyl)-HCID 44419034,5-Dinitrobenzene-1,2-diamine

生成物 1

HCID 223412132-(3,4-Dichlorophenyl)-6,7-dinitroquinoxaline

試薬・触媒・溶媒 1

HCID 679Dimethyl Sulfoxide溶媒

反応条件

温度
55 °C

実験手順

48% aqueous HBr (8.8 M) (3.4 ml, 30 mmol) was slowly added to a stirred solution of 3,4-dichloroacetophenone (1.89 g, 10 mmol) in DMSO (17 ml). The solution was stirred in an open flask at 55° C. for 24 hours. The solution was poured onto ice, the solid product was filtered, washed with water, and redissolved in ethanol (18 ml). 4,5-Dinitro-1,2-phenylene-diamine (890 mg, 4.5 mmol) was added and the mixture was heated to reflux for 4 hours.

後処理

  1. additionThe solution was poured onto ice
  2. filtrationthe solid product was filtered
  3. washwashed with water
  4. dissolutionredissolved in ethanol (18 ml)
  5. temperaturethe mixture was heated
  6. temperatureto reflux for 4 hours

出典と根拠

ORDレコード
ord-a20703e9de084538bfee31fbd1896e79
出典データセット
uspto-grants-2005_08
特許番号
US06927214B1

関連ノート

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