Acetic Anhydride → N-(2-methylquinolin-6-yl)acetamide
反応式
[NH2:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH3:12])[CH:6]=[CH:5]2.[C:13](OC(=O)C)(=[O:15])[CH3:14]>N1C=CC=CC=1>[CH3:12][C:7]1[CH:6]=[CH:5][C:4]2[C:9](=[CH:10][CH:11]=[C:2]([NH:1][C:13](=[O:15])[CH3:14])[CH:3]=2)[N:8]=1参加物
4
実験手順
6-amino-2-methylquinoline (1.02 g, 6.45 mmol) was dissolved in pyridine (30 ml), acetic anhydride (0.913 ml, 9.67 mmol) was added thereto, and the mixture was stirred at room temperature for 3 hours. The solvent was distilled off under reduced pressure, and diisopropyl ether was added thereto for crystallization, to obtain N-(2-methyl-6-quinolinyl)acetamide (1.20 g) as white powders.
後処理
- distillationThe solvent was distilled off under reduced pressure, and diisopropyl ether
- additionwas added
- customfor crystallization
出典と根拠
- ORDレコード
- ord-7b10ee4da1b94f538075e3dc4a4d25ca
- 出典データセット
- uspto-grants-2005_08
- 特許番号
- US06930185B2
反応ノート
読み込み中…