Nitric Acid → 1-Nitro-2,5-bis(trifluoromethyl)benzene

HRID 585333

反応式

HRID 585333 の反応式
[F:1][C:2]([F:14])([F:13])[C:3]1[CH:8]=[CH:7][C:6]([C:9]([F:12])([F:11])[F:10])=[CH:5][CH:4]=1.[N+:15]([O-])([OH:17])=[O:16]>S(=O)(=O)(O)O>[F:1][C:2]([F:13])([F:14])[C:3]1[CH:4]=[CH:5][C:6]([C:9]([F:10])([F:11])[F:12])=[CH:7][C:8]=1[N+:15]([O-:17])=[O:16]

参加物

4

反応物 2

HCID 944Nitric AcidHCID 679451,4-Bis(trifluoromethyl)benzene

生成物 1

HCID 27340481-Nitro-2,5-bis(trifluoromethyl)benzene収率 35%

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

A process of nitrating 1,4-bis(trifluoromethyl)benzene by means of 100 mass % nitric acid at from 90 to 105° C. by using 24% fuming sulfuric acid as a solvent to obtain 2,5-bis(trifluoromethyl)nitrobenzene in a yield of 35% (J. Amer. Chem. Soc., 75, 4967 (1953)).

後処理

  1. customat from 90 to 105° C.

出典と根拠

ORDレコード
ord-a644530108b94ad983475f442eb57f48
出典データセット
uspto-grants-2005_08
特許番号
US06930214B2

関連ノート

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