Carbazole → 9-Acetyl-9H-carbazole

HRID 585576

反応式

HRID 585576 の反応式
[CH:1]1[C:13]2[NH:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.B(F)(F)F.[CH3:18][CH2:19][O:20]CC>C(OC(=O)C)(=O)C>[C:19]([N:12]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[C:13]1=[CH:1][CH:2]=[CH:3][CH:4]=2)(=[O:20])[CH3:18]

参加物

4

反応物 2

HCID 6854CarbazoleHCID 8000Boron trifluoride etherate

生成物 1

HCID 958379-Acetyl-9H-carbazole

試薬・触媒・溶媒 1

HCID 7918Acetic Anhydride溶媒

反応条件

温度
0 °C

実験手順

Carbazole (100.24 g) was suspended in acetic anhydride (300 mL) with catalytic boron trifluoride etherate (0.65 mL) and the solution refluxed for 25 min. then cooled to 0° C. and the solid was then collected and recrystallized from hexane to give 82.65 g 9-acetyl-carbazole.

後処理

  1. temperaturethe solution refluxed for 25 min.
  2. customthe solid was then collected
  3. customrecrystallized from hexane

出典と根拠

ORDレコード
ord-8a1ad62710b141d79605e933886c8933
出典データセット
uspto-grants-2005_08
特許番号
US06933314B2

関連ノート

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