Thionyl Chloride → 2-(4-Chlorophenyl)-2-methylpropanoyl chloride

HRID 586056ノート

反応式

HRID 586056 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:13])([CH3:12])[C:9](O)=[O:10])=[CH:4][CH:3]=1.S(Cl)([Cl:16])=O>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:13])([CH3:12])[C:9]([Cl:16])=[O:10])=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 804062-(4-Chlorophenyl)-2-methylpropionic acid

生成物 1

HCID 135368632-(4-Chlorophenyl)-2-methylpropanoyl chloride

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

2-(4-Chlorophenyl)-2-methylpropanoic acid (3.85 g, 19.4 mmol) in toluene (5 mL) and thionyl chloride (5.00 g, 3.1 mL) was heated at 80° C. for 2 hours. The mixture was cooled and concentrated under reduced pressure to provide the title compound.

後処理

  1. temperatureThe mixture was cooled
  2. concentrationconcentrated under reduced pressure

出典と根拠

ORDレコード
ord-e1369f3beefb40839e681d647c5c4b1a
出典データセット
uspto-grants-2005_08
特許番号
US06933311B2

反応ノート

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