関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1-Fluoro-3-nitrobenzene | HCID 9823 | — |
| 反応物 | 1-Methylpiperazine | HCID 53167 | — |
| 生成物 | 1-Methyl-4-(3-nitrophenyl)piperazine | HCID 12152161 | — |
反応手順
A mixture of 3-fluoronitrobenzene (20 ml; 0.19 mol) and 1-methylpiperazine (40 ml; 0.36 mol) was heated to 120° C. for a week. The cooled mixture was purified by column-chromatography on silica gel using a mixture of ethyl acetate and methanol (9:1 v/1) as the eluent. Yield: 33 g (79%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06936613B2 |
|---|
| 出典データセット | uspto-grants-2005_08 |
|---|
| ORD ID | ord-ee474b006a704546bf9351a9bd8a51d2 |
|---|
| 出典メモ | uspto-grants-2005_08 |
|---|
