Furfural → (2,6-Dimethyl-phenyl)-(5-furan-2-yl-imidazo[1,2-b][1,2,4]triazol-6-yl)-amine

HRID 586575

反応式

HRID 586575 の反応式
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[CH3:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:9]=1[N+:15]#[C-:16].[CH:17](=O)[C:18]1[O:22][CH:21]=[CH:20][CH:19]=1>Cl(O)(=O)(=O)=O>[CH3:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:9]=1[NH:15][C:16]1[N:3]2[NH:4][CH:5]=[N:6][C:2]2=[N:1][C:17]=1[C:18]1[O:22][CH:21]=[CH:20][CH:19]=1

参加物

5

反応物 3

HCID 7362FurfuralHCID 760092,6-Dimethylphenyl isocyanideHCID 178418311HCID 178418311、化合物

生成物 1

HCID 22335545(2,6-Dimethyl-phenyl)-(5-furan-2-yl-imidazo[1,2-b][1,2,4]triazol-6-yl)-amine

試薬・触媒・溶媒 1

HCID 24247Perchloric Acid溶媒

実験手順

Compound 18 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 3-amino-1,2,4-triazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) 2,6-dimethylphenylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) furfural solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.

出典と根拠

ORDレコード
ord-3f363ae7e8454a0f82478b7bcceedee1
出典データセット
uspto-grants-2005_08
特許番号
US06936631B2

関連ノート

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