Iodoethane → HCID 69737384、化合物

反応式

[CH3:1][O:2][CH2:3][CH:4]1[C@H:6]([CH2:7][OH:8])[C:5]1([CH3:23])[C:9]1[CH:18]=[CH:17][C:16]2[C:15]([CH3:20])([CH3:19])[CH2:14][CH2:13][C:12]([CH3:22])([CH3:21])[C:11]=2[CH:10]=1.[CH2:24](I)C>>[CH2:1]([O:2][CH2:3][CH:4]1[C@H:6]([CH2:7][OH:8])[C:5]1([CH3:23])[C:9]1[CH:18]=[CH:17][C:16]2[C:15]([CH3:20])([CH3:19])[CH2:14][CH2:13][C:12]([CH3:22])([CH3:21])[C:11]=2[CH:10]=1)[CH3:24]

参加物

反応物 2

HCID 6340Iodoethane

HCID 69738373HCID 69738373、化合物

生成物 1

HCID 69737384HCID 69737384、化合物収率 78%

実験手順

Following a procedure similar to that for the preparation of Intermediate 6a using Intermediate 4 as the starting material and ethyl iodide as alkylating reagent yielded the title compound as a colorless oil (69 mg, 78% yield):

出典と根拠

ORDレコード: ord-195b8beebbae4ac1acdaa614980006b3
出典データセット: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06936636B2

反応ノート

読み込み中…