HCID 58577265、化合物 → 3-N-methylpyridine-2,3-diamine
反応式
[CH2:1]([N:8](C)[C:9]1[C:10]([N+:15]([O-])=O)=[N:11][CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1>CCO.[Pd]>[CH3:1][NH:8][C:9]1[C:10]([NH2:15])=[N:11][CH:12]=[CH:13][CH:14]=1参加物
4
実験手順
A mixture of N-benzyl-N-methyl-2-nitropyridin-3-amine (2.6 g) and 10% Pd—C (0.569 g) in EtOH (50 mL) was hydrogenated under balloon pressure at room temperature over weekend. The catalyst was removed by filtration and the filtrate was concentrated in vacuo to give N3-methylpyridine-2,3-diamine (1.14 g) as pale yellow oil.
後処理
- waitwas hydrogenated under balloon pressure at room temperature over weekend
- customThe catalyst was removed by filtration
- concentrationthe filtrate was concentrated in vacuo
出典と根拠
- ORDレコード
- ord-5f5b2d67b8434796a33c7e1d471a6136
- 出典データセット
- uspto-grants-2016_01
- 特許番号
- US09226921B2
反応ノート
読み込み中…