関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | Methyl 2,3-dihydro-2-oxo-1H-indole-5-carboxylate | HCID 2773516 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-Oxoindoline-5-carbohydrazide | HCID 90418397 | 63% |
反応手順
To a solution of methyl 2-oxoindoline-5-carboxylate (0.40 g, 4.8 mmol) in EtOH (8 ml) was added hydrazine monohydrate (2 ml), and the mixture was stirred for 6 h at 80° C. The mixture was cooled to room temperature, and the resulting precipitate was filtered and dried to afford 2-oxoindoline-5-carbohydrazide (0.25 g, 63%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09227962B2 |
|---|
| 出典データセット | uspto-grants-2016_01 |
|---|
| ORD ID | ord-e5342dc332474d8a8f7145d33e1718e3 |
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| 出典メモ | uspto-grants-2016_01 |
|---|
