Methanol → 3-Bromotricyclo[3.3.1.13,7]decane-1-methanol
反応式
O1CCCC1.B.CO.[Br:9][C:10]12[CH2:19][CH:14]3[CH2:15][CH:16]([CH2:18][C:12]([C:20](O)=[O:21])([CH2:13]3)[CH2:11]1)[CH2:17]2>O1CCCC1>[Br:9][C:10]12[CH2:19][CH:14]3[CH2:15][CH:16]([CH2:18][C:12]([CH2:20][OH:21])([CH2:13]3)[CH2:11]1)[CH2:17]2参加物
5
実験手順
In a 250 ml round-bottomed flask, 3-bromoadamantane-1-carboxylic acid (7.89 g) was dissolved in tetrahydrofuran (30 mL). Borane tetrahydrofuran complex (1M in hexane, 60 mL) was added slowly. The mixture was stirred at room temperature overnight. Methanol (20 mL) was added to the solution slowly. After removal of the solvents, methanol (5 mL) was added to the oily residue. Removal of the solvent provided the title compound.
後処理
- customAfter removal of the solvents, methanol (5 mL)
- additionwas added to the oily residue
- customRemoval of the solvent
出典と根拠
- ORDレコード
- ord-e6c059fa17084a0aa24924dd56f1effb
- 出典データセット
- uspto-grants-2016_01
- 特許番号
- US09227963B2
反応ノート
読み込み中…