Styrene → P-Methoxystilbene

反応式

I[C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][CH:3]=1.[CH2:10]=[CH:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.C(N(CC)CC)C>>[CH3:9][O:8][C:5]1[CH:6]=[CH:7][C:2](/[CH:10]=[CH:11]/[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:3][CH:4]=1

参加物

反応物 3

HCID 7501Styrene

HCID 8471Triethylamine

HCID 696764-Iodoanisole

生成物 1

HCID 1245920P-Methoxystilbene

実験手順

4-Iodoanisole (58 mg, 0.25 mmol) and styrene (43 μL, 0.375 mmol) were coupled using the procedure described above, but using triethylamine (0.375 mmol, 52 μL) in place of ethyldiisopropylamine, to give 100% conversion to (E)-4-methoxystilbene by GC analysis.

出典と根拠

ORDレコード: ord-7ae5b94b9af240a9831caff3bee98b17
出典データセット: uspto-grants-2016_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09233366B2

反応ノート

読み込み中…