Formaldehyde → 3-(Hydroxymethyl)benzoselenazolinone

HRID 5918ノート

反応式

HRID 5918 の反応式
[Se:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH2:10]=[O:11].C[OH:13]>O>[OH:11][CH2:10][N:3]1[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[Se:1](=[O:13])[CH2:2]1

参加物

5

反応物 3

HCID 712FormaldehydeHCID 887MethanolHCID 136087Benzoselenazole

生成物 1

HCID 867472283-(Hydroxymethyl)benzoselenazolinone

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
40 °C

実験手順

2 grams (0.01 mol) of benzoselenazoline, 2 cm3 (0.02 mol) of aqueous formaldehyde solution and 2 cm3 of methanol are introduced into a ground-necked flask. The mixture is brought to reflux two hours. After cooling to 40° C. 20 cm3 of water are added. The mixture is allowed to cool and the product is drained, washed with water, dried and recrystallized in cyclohexane.

後処理

  1. temperatureto reflux two hours
  2. temperatureto cool
  3. washwashed with water
  4. customdried
  5. customrecrystallized in cyclohexane

出典と根拠

ORDレコード
ord-5d28e8e0676841e598914b8d0977a4cb
出典データセット
uspto-grants-1993_09
特許番号
US05246951

反応ノート

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