1,2-Dichlorobenzene → 3,5-Diallyl-4-hydroxybenzoic acid methyl ester
反応式
[CH2:1]([C:4]1[CH:5]=[C:6]([CH:11]=[CH:12][C:13]=1[O:14]CC=C)[C:7]([O:9][CH3:10])=[O:8])[CH:2]=[CH2:3].C(OCC)(=O)C.Cl[C:25]1[CH:30]=CC=C[C:26]=1Cl>CCCCCC>[OH:14][C:13]1[C:12]([CH2:30][CH:25]=[CH2:26])=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][C:4]=1[CH2:1][CH:2]=[CH2:3]参加物
5
実験手順
The product of Step A (3.2 g, 13.8 mmol) was refluxed in 1,2-dichlorobenzene for 3 days in the presence of a catalytic amount of BHT (10 mg). Flash column chromatography of the mixture using hexane and then 10% and 20% ethyl acetate in hexane afforded 3.1 g (97%) of the title compound.
出典と根拠
- ORDレコード
- ord-3170c5d6164841af935791c864839bf7
- 出典データセット
- uspto-grants-1993_09
- 特許番号
- US05246944
反応ノート
読み込み中…