3-Chloro-4-methylaniline → (3-Chloro-4-methylphenyl)hydrazine

HRID 59385

反応式

HRID 59385 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1[CH3:9])[NH2:5].[N:10]([O-])=O.[Na+].O.O.Cl[Sn]Cl>Cl>[Cl:1][C:2]1[CH:3]=[C:4]([NH:5][NH2:10])[CH:6]=[CH:7][C:8]=1[CH3:9]

参加物

5

反応物 3

HCID 72553-Chloro-4-methylanilineHCID 61436Stannous chloride dihydrateHCID 23668193Sodium Nitrite

生成物 1

HCID 292017(3-Chloro-4-methylphenyl)hydrazine収率 68,412.602%

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

The title compound was prepared according to the procedure described in step-1 of Intermediate-61 by using 3-chloro-4-methylaniline (6.0 g, 0.0420 mmol), NaNO2 (8.56 g, 0.050 mmol), SnCl2.2H2O (23.7 g, 0.105 mmol) and conc. HCl (100 mL) to afford 4.5 g of the desired product.

後処理

  1. customThe title compound was prepared

出典と根拠

ORDレコード
ord-e122a62c34bf4e92874365984c726a1c
出典データセット
uspto-grants-2016_09
特許番号
US09439890B2

関連ノート

読み込み中…