Sodium hydride → tert-butyl cis-3-fluoro-4-((4-(N-isobutyl-N-(5-isopropyl-3-methylpyridin-2-yl)sulfamoyl)phenoxy)methyl)piperidine-1-carboxylate

反応式

F[C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]([CH2:22][CH:23]([CH3:25])[CH3:24])[C:12]2[C:17]([CH3:18])=[CH:16][C:15]([CH:19]([CH3:21])[CH3:20])=[CH:14][N:13]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[H-].[Na+].[F:28][C@H:29]1[C@@H:34]([CH2:35][OH:36])[CH2:33][CH2:32][N:31]([C:37]([O:39][C:40]([CH3:43])([CH3:42])[CH3:41])=[O:38])[CH2:30]1>CN(C)C=O>[F:28][C@H:29]1[C@@H:34]([CH2:35][O:36][C:2]2[CH:7]=[CH:6][C:5]([S:8](=[O:9])(=[O:10])[N:11]([CH2:22][CH:23]([CH3:25])[CH3:24])[C:12]3[C:17]([CH3:18])=[CH:16][C:15]([CH:19]([CH3:20])[CH3:21])=[CH:14][N:13]=3)=[CH:4][CH:3]=2)[CH2:33][CH2:32][N:31]([C:37]([O:39][C:40]([CH3:43])([CH3:42])[CH3:41])=[O:38])[CH2:30]1