HCID 69084602、化合物 → 3-(1H-1,2,3-triazol-1-yl)benzaldehyde

HRID 594252ノート

反応式

HRID 594252 の反応式
[N:1]1([C:6]2[CH:7]=[C:8]([CH2:12][OH:13])[CH:9]=[CH:10][CH:11]=2)[CH:5]=[CH:4][N:3]=[N:2]1>C(Cl)Cl.O=[Mn]=O>[N:1]1([C:6]2[CH:7]=[C:8]([CH:9]=[CH:10][CH:11]=2)[CH:12]=[O:13])[CH:5]=[CH:4][N:3]=[N:2]1

参加物

4

反応物 1

HCID 69084602HCID 69084602、化合物

生成物 1

HCID 834815293-(1H-1,2,3-triazol-1-yl)benzaldehyde

試薬・触媒・溶媒 2

HCID 14801Manganese dioxide触媒HCID 6344Dichloromethane溶媒

実験手順

A solution of (3-(1H-1,2,3-triazol-1-yl)phenyl)methanol (55 mg; 0.31 mmol) in anh. DCM (1 ml) was treated with MnO2 (411 mg; 4.73 mmol), and the resulting mixture was stirred at rt, under nitrogen, for 2 h. The resulting reaction mixture was then filtered over celite, and the separated solids were washed with DCM. The filtrate was concentrated to dryness under reduced pressure giving 3-(1H-1,2,3-triazol-1-yl)benzaldehyde as a colorless solid. LC-MS (conditions A): tR=0.45 min.; [M+H]+: 174.09 g/mol.

後処理

  1. customThe resulting reaction mixture
  2. filtrationwas then filtered over celite
  3. washthe separated solids were washed with DCM
  4. concentrationThe filtrate was concentrated to dryness under reduced pressure

出典と根拠

ORDレコード
ord-30590ce99abd4e7d956920c9f258784d
出典データセット
uspto-grants-2016_01
特許番号
US09242970B2

反応ノート

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