Dichloromethane → tert-butyl 4-(3-amino-6-(3,6-dihydro-2H-pyran-4-yl)pyrazin-2-yl)-2-fluorobenzoate

反応式

[NH2:1][C:2]1[C:3]([C:9]2[CH:21]=[CH:20][C:12]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])=[C:11]([F:22])[CH:10]=2)=[N:4][C:5](Br)=[CH:6][N:7]=1.C(Cl)Cl.[C:26]1(B2OC(C)(C)C(C)(C)O2)[CH2:31][CH2:30][CH2:29][CH2:28]C=1.C(OCC)(=[O:43])C>COCCOC.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>[NH2:1][C:2]1[C:3]([C:9]2[CH:21]=[CH:20][C:12]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])=[C:11]([F:22])[CH:10]=2)=[N:4][C:5]([C:30]2[CH2:31][CH2:26][O:43][CH2:28][CH:29]=2)=[CH:6][N:7]=1