Dimethyl Sulfate → HCID 22452645、化合物

HRID 596590ノート

反応式

HRID 596590 の反応式
[OH:1][C:2]1[CH:3]=[C:4]([C:12]([OH:14])=[O:13])[C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1.[OH-].[Na+].[CH3:17]OS(OC)(=O)=O>>[CH3:17][O:1][C:2]1[CH:3]=[C:4]([C:12]([OH:14])=[O:13])[C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1

参加物

4

反応物 3

HCID 6497Dimethyl SulfateHCID 14798Sodium HydroxideHCID 21450344HCID 21450344、化合物

生成物 1

HCID 22452645HCID 22452645、化合物

実験手順

A mixture of 0.02 mole of 3-hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid, and 40 ml. of 2 N sodium hydroxide solution is treated with 0.04 mole of dimethylsulfate over a 5 minutes period, and the mixture is stirred for 24 hours. The mixture is washed with 3 × 50 ml. of ether and acidified with dilute hydrochloric acid. The precipitate is collected, washed with water, dried at room temperature and 100μ pressure and recrystallized from cyclohexane.

後処理

  1. washThe mixture is washed with 3 × 50 ml
  2. customThe precipitate is collected
  3. washwashed with water
  4. customdried at room temperature
  5. custom100μ pressure and recrystallized from cyclohexane

出典と根拠

ORDレコード
ord-be87bbe540cf4fb5b9c31419c109741a
出典データセット
uspto-grants-1977_03
特許番号
US04011326

反応ノート

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