5-[p-(1-Cyclooctenyl)-phenoxy]-pentanoic acid ethyl ester → 5-(p-Cyclooctyl-phenoxy)-pentanoic acid ethyl ester

HRID 597306

反応式

HRID 597306 の反応式
[CH2:1]([O:3][C:4](=[O:24])[CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH:17]=2)=[CH:12][CH:11]=1)[CH3:2].[H][H]>[Pd].C(O)C>[CH2:1]([O:3][C:4](=[O:24])[CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([CH:16]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)=[CH:12][CH:11]=1)[CH3:2]

参加物

5

反応物 2

HCID 543745795-[p-(1-Cyclooctenyl)-phenoxy]-pentanoic acid ethyl esterHCID 178418361HCID 178418361、化合物

生成物 1

HCID 543712055-(p-Cyclooctyl-phenoxy)-pentanoic acid ethyl ester

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

2 g of palladium on charcoal (5% strength) are added to a solution of 20 g of 5-[p-(1-cyclooctenyl)-phenoxy]-pentanoic acid ethyl ester in 100 ml of ethanol and hydrogenation is carried out at room temperature and normal pressure until one equivalent of hydrogen has been absorbed. The catalyst is then filtered off and the filtrate is evaporated to dryness in vacuo. Distillation of the evaporation residue in a high vacuum gives 5-(p-cyclooctyl-phenoxy)-pentanoic acid ethyl ester of boiling point 170° -175° C at 0.05 mm Hg.

後処理

  1. customis carried out at room temperature
  2. filtrationThe catalyst is then filtered off
  3. customthe filtrate is evaporated to dryness in vacuo
  4. distillationDistillation of the evaporation residue in a high vacuum

出典と根拠

ORDレコード
ord-f98040b25c974e0393e288e063af74d1
出典データセット
uspto-grants-1977_03
特許番号
US04013708

関連ノート

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