Pyridine → Carbonochloridic acid, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester

HRID 597384

反応式

HRID 597384 の反応式
N1C=CC=CC=1.[CH3:7][C:8]1([CH3:18])[CH2:12][C:11]2[CH:13]=[CH:14][CH:15]=[C:16]([OH:17])[C:10]=2[O:9]1.[C:19](Cl)([Cl:21])=[O:20]>C1C=CC=CC=1>[Cl:21][C:19]([O:17][C:16]1[C:10]2[O:9][C:8]([CH3:18])([CH3:7])[CH2:12][C:11]=2[CH:13]=[CH:14][CH:15]=1)=[O:20]

参加物

5

反応物 3

HCID 1049PyridineHCID 6371PhosgeneHCID 152782,3-Dihydro-2,2-dimethyl-7-benzofuranol

生成物 1

HCID 10987969Carbonochloridic acid, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

反応条件

温度
25 °C

実験手順

A 7.9 g. (0.1 mol) sample of pyridine was added dropwise to a solution of 16.4 g. (0.1 mol) 2,3-dihydro-2,2-dimethyl-7-benzofuranol and 9.9 g. (0.1 mol) phosgene in 100 ml. benzene at about 25° C. The reaction mixture was stirred at 25° C for 2 hours, filtered and evaporated under reduced pressure. The solid residue was washed with hexane and dried to give the product, m.p. 85°-87.5° C. Elemental analysis for C11H11O3Cl showed:

後処理

  1. customat about 25° C
  2. filtrationfiltered
  3. customevaporated under reduced pressure
  4. washThe solid residue was washed with hexane
  5. customdried
  6. customto give the product, m.p. 85°-87.5° C

出典と根拠

ORDレコード
ord-6925c25ebcbc4de39f3d43df65e76a8b
出典データセット
uspto-grants-1977_03
特許番号
US04013774

関連ノート

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