Acetic Anhydride → 3-Allyl-4-acetoxy-cinnamic acid
反応式
[CH2:1]([C:4]1[CH:5]=[C:6]([CH:12]=[CH:13][C:14]=1[OH:15])[CH:7]=[CH:8][C:9]([OH:11])=[O:10])[CH:2]=[CH2:3].[C:16](OC(=O)C)(=[O:18])[CH3:17]>[OH-].[Na+]>[CH2:1]([C:4]1[CH:5]=[C:6]([CH:12]=[CH:13][C:14]=1[O:15][C:16](=[O:18])[CH3:17])[CH:7]=[CH:8][C:9]([OH:11])=[O:10])[CH:2]=[CH2:3]参加物
4
実験手順
118 g (0.058 mol) of 3-allyl-4-hydroxy-cinnamic acid are dissolved in 580 ml of 2 N sodium hydroxide solution, 800 g of ice are added and 120 g (1.16 mols) of acetic anhydride are introduced dropwise over the course of 15 minutes at 0°-5°C, whilst stirring. The crystals which have precipitated are then separated off, suction-dried and recrystallised from ethyl acetate. 3-Allyl-4-acetoxy-cinnamic acid of melting point 143°-144°C is thus obtained.
後処理
- customThe crystals which have precipitated
- customare then separated off
- customsuction-dried
- customrecrystallised from ethyl acetate
出典と根拠
- ORDレコード
- ord-0bfefdbb0fd44876abb7c41d6595340e
- 出典データセット
- uspto-grants-1977_03
- 特許番号
- US04014920
反応ノート
読み込み中…