Potassium ethylxanthate → HCID 178505601、化合物
反応式
[NH2:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[OH:9].CCO[C:13]([S-])=[S:14].[K+]>CO>[F:8][C:7]1[C:2]2[N:1]=[C:13]([SH:14])[O:9][C:3]=2[CH:4]=[CH:5][CH:6]=1参加物
4
反応条件
- 温度
- 70 °C
実験手順
A mixture of 1 g (7.867 mmol) 2-amino-3-fluorophenol and 1.42 g (8.654 mmol) potassium ethylxanthogenate in 28 mL methanol was heated in a 70° C. oil bath for 3 h. The solvent was removed in vacuo. The residue was dissolved in 50 mL water. The aqueous layer was acidified with HCl 2N. The solid was filtered, washed with water and dried to provide 568 mg (42.7%) of the title compound as a light grey solid. MS(m/e): 168.0 (M−H+).
後処理
- customThe solvent was removed in vacuo
- dissolutionThe residue was dissolved in 50 mL water
- filtrationThe solid was filtered
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-eb344cf9a5754001af6c2f36b5311ef4
- 出典データセット
- uspto-grants-2011_03
- 特許番号
- US07897627B2
反応ノート
読み込み中…