Hydrochloric Acid → HCID 178505403、化合物
反応式
F[C:2]1[CH:8]=[C:7]([F:9])[C:6]([F:10])=[CH:5][C:3]=1[NH2:4].CCO[C:14]([S-:16])=[S:15].[K+].Cl>CN(C)C=O.O>[F:10][C:6]1[C:7]([F:9])=[CH:8][C:2]2[S:15][C:14]([SH:16])=[N:4][C:3]=2[CH:5]=1参加物
6
反応条件
- 温度
- 95 °C
実験手順
A mixture of 1 g (6.80 mmol) 2,4,5-trifluoroaniline and 1.33 g (8.16 mmol) potassium ethylxanthogenate in 5 mL dry N,N-dimethylformamide was heated in a 95° C. oil bath for 7 h. The reaction mixture was cooled to room temperature and diluted with water (15 mL). The mixture was acidified with aqueous HCl 2N. The precipitate was collected by filtration, washed with water and dried to provide 0.55 g (40%) of the titled compound as a light yellow solid. MS(m/e): 201.9 (M−H+).
後処理
- temperatureThe reaction mixture was cooled to room temperature
- filtrationThe precipitate was collected by filtration
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-8b9c6fe51079404f9f89c6c44a44a38b
- 出典データセット
- uspto-grants-2011_03
- 特許番号
- US07897627B2
反応ノート
読み込み中…