HCID 59379802、化合物 → HCID 59379814、化合物

HRID 598748ノート

反応式

HRID 598748 の反応式
[CH3:1][O:2][C:3](=[O:25])[C:4]([C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([O:16][CH2:17][CH2:18][N:19]2[CH2:24][CH2:23][O:22][CH2:21][CH2:20]2)=[CH:8][CH:7]=1)=[O:5]>CO.[Pd]>[CH3:1][O:2][C:3](=[O:25])[CH:4]([OH:5])[C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([O:16][CH2:17][CH2:18][N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)=[CH:8][CH:7]=1

参加物

4

反応物 1

HCID 59379802HCID 59379802、化合物

生成物 1

HCID 59379814HCID 59379814、化合物

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 23938Palladium溶媒

実験手順

To a solution of 12 (1 g, 2.9 mmol) in MeOH (10 mL), Pd/C (10 wt %) was added and the mixture stirred at rt under H2 atmosphere. Upon completion of the reaction (monitored by LCMS), the mixture was filtered through celite and the filtrate evaporated to give a yellow oil which solidified upon standing. Calculated mass=345. Observed mass=345.

後処理

  1. customUpon completion of the reaction (monitored by LCMS)
  2. filtrationthe mixture was filtered through celite
  3. customthe filtrate evaporated
  4. customto give a yellow oil which

出典と根拠

ORDレコード
ord-4a4637a108dd4243855c9e7ec6d2251d
出典データセット
uspto-grants-2011_03
特許番号
US07897599B2

反応ノート

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